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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
22.73
Human Site:
Y39
Identified Species:
35.71
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
Y39
Q
P
E
E
I
W
L
Y
K
N
P
L
V
Q
S
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
L98
E
V
G
V
R
L
A
L
F
A
A
F
L
V
T
Dog
Lupus familis
XP_535038
333
36609
Y101
Q
P
E
E
I
W
L
Y
K
N
P
L
V
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
Y39
Q
P
E
E
I
W
L
Y
K
N
P
L
V
Q
S
Rat
Rattus norvegicus
O08564
282
31978
G37
R
H
T
P
F
Q
R
G
V
F
C
T
D
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
Y45
Q
P
E
E
I
W
L
Y
K
N
P
L
V
Q
S
Chicken
Gallus gallus
XP_426544
322
36285
Y90
Q
P
E
E
I
W
L
Y
K
N
P
L
V
Q
S
Frog
Xenopus laevis
Q6GQ62
226
25153
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
Y46
Q
P
E
E
L
W
L
Y
K
N
P
L
V
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
F36
E
L
E
K
A
E
P
F
T
R
I
I
H
E
D
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
F90
L
N
A
A
T
V
L
F
V
E
Y
Y
R
M
Q
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
R26
E
E
L
D
P
F
Q
R
V
I
Q
P
E
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
R58
E
D
M
L
T
D
L
R
Y
P
L
Q
D
N
T
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
P55
N
D
L
T
I
S
H
P
Y
A
T
T
E
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
0
0
100
N.A.
100
6.6
N.A.
100
100
0
86.6
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
0
20
100
N.A.
100
20
N.A.
100
100
0
100
N.A.
N.A.
40
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
0
7
0
0
14
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
14
0
7
0
7
0
0
0
0
0
0
14
0
7
% D
% Glu:
27
7
47
40
0
7
0
0
0
7
0
0
14
27
0
% E
% Phe:
0
0
0
0
7
7
0
14
7
7
0
7
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
40
0
0
0
0
7
7
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
40
0
0
0
0
0
0
% K
% Leu:
7
7
14
7
7
7
54
7
0
0
7
40
7
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
7
7
0
0
0
0
0
0
0
40
0
0
0
7
0
% N
% Pro:
0
40
0
7
7
0
7
7
0
7
40
7
0
0
0
% P
% Gln:
40
0
0
0
0
7
7
0
0
0
7
7
0
34
7
% Q
% Arg:
7
0
0
0
7
0
7
14
0
7
0
0
7
7
0
% R
% Ser:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
47
% S
% Thr:
0
0
7
7
14
0
0
0
7
0
7
14
0
0
14
% T
% Val:
0
7
0
7
0
7
0
0
20
0
0
0
40
7
7
% V
% Trp:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
14
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _